D-Dimer level as a Predictor of Covid-19 Severity
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Abstract
Background: Coagulopathy has been reported with COVID-19 Illness with D-Dimer elevations in roughly half the patients.
Objectives: To evaluate the outcomes of patients havingCOVID-19for their disease severity with D-Dimers as a marker for the prediction of the disease.
Study Design: Cross sectional / Observational study.
Place and Duration of Study: The study was performed in the Department of Medicine at Khyber Medical College/Teaching Hospital Peshawar from January 2021 to March 2021.
Methodology: A total of 110 patients were included in the study. Patients were divided into two groups; DM group included the D-Dimer levels of the patients with the Mild to Moderate Illness. DS group included the D-Dimer levels of the patients with the severe illness.All information was recorded using proforma and analysed on SPSS for MacBook, 26.0.
Results: Linear regression analysis showed that D-Dimer level was a significant predictor of disease severity (Adjusted R Square = .888). D-Dimer was 110±31 (ng/ml) for DM group and 457±149(ng/ml) for DS group.
Conclusion:D-Dimer levels done early on predict high risk of pulmonary complications and thromboembolic episodes which could be prevented by therapy initiation and intervention.