A Chronic Thromboembolic Pulmonary Hypertension (CTEPH): A Case Report from Indonesia

Abstract

Pulmonary hypertension (PH) is hemodynamically defined as a mPAP≥25 mmHg at rest. Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive form of PH as a consequence of chronic thromboembolic disease that leads to prolonged occlusion of the pulmonary vascular. The precise incidence of CTEPH is unknown. Untreated CTEPH could develop progressive disease with a high mortality due to right heart failure;hence, all patients should receive proper treatment. We report a case of a-48-year-old woman diagnosed with pulmonary embolism through thorax computed tomography scan and detected with severe pulmonary hypertension. The patient was then treated with long term oral anticoagulant and pulmonary artery hypertension (PAH)-targeted therapy. CTEPH may represent the final manifestation of unresolved pulmonary embolism. The current treatments for CTEPH include pulmonary endarterectomy, long term anticoagulation, lung transplant, balloon pulmonary angioplasty,and soluble guanylate cyclase stimulator for selected patient.