Wound Healing Studies of Selected Euphorbia Species: A Review

Abstract

For thousands of years, nature has been the source of medicine, and a huge number of modern marketed drugs which  isolated from  natural remidies  were discovered  depending on its  useses in traditional medicine. Wound healing possesses is still the great challenge for the medical community. According to the WHO, more than 80% of world population utilized traditional remedies as alternative medicine for wound healing treatment . This work focus on the Euphorbia species plants (belong to Euphorbiaceae family) which have wound healing activity. Published previous studies  on the wound healing property of Euphorbia species plants was gathered by the use of different scientific websites such as Google Scholar, PubMed, Science Direct, and Web of Knowledge. This review identified plants from species of Euphorbia that promote wound healing. The   selected plants are with high content of flavonoids, saponins, steroids, triterpenoid and tannins. At the same time these components reportedly promote wound healing by different pharmacological activity like mopping of reactive oxygen species from wounded tissues, inhibition / cidal effects against infections that delay wound healing and anti-inflammatory activities. These plant could be considered as future drug candidates for wound healing for healing of wounds.