Linum Usitatissimum : Molecular Modelling of Its Protein and Analysis of Phytoconstituents

Abstract

Breast cancer is one of the most prevalent cancers globally and the second most responsible for cancer mortality. Flaxseed was one of the largest foods most researched with possible breast cancer interactions, but mainly in animal laboratory studies, but only in a few clinical trials. It is rich in omega 3, alpha-linolenic acid, lignan, and fiber fatty acids. One of the main components of flaxseed is lignans, of which 95 percent are made from secoisolariciresinol, a predominant diglucoside (SDG). SDG is converted into enterolactone and enterodiol, both with anti-estrogen. The structure of behaviour and estrogen-like; they can bind to cell receptors, reducing cell growth. In this study, plant sampling was performed with an anti-VEGF modulatory feature. Phytochemicals have been isolated from PubChem in these processes and docked into mutants of the PBD protein. There are no significant effects on the fatty acid content of flaxseed oil from mucilage and drying. However, these procedures increased the content of total phenols and total sterols while reducing the pigment content of carotenoids. More research, specifically clinical studies, is required that could demonstrate the potential benefits of flaxseed for breast cancer. In this study, on the basis of binding affinity of lignan with VEGF receptors further analysis of the Phytoconstituents has been done.