Transcranial Doppler Assessment of Cerebrovascular Reactivity in patients of migraine

Abstract

Background:Migraine is a common, chronic, multifactorial neurovascular disorder typically characterized by recurrent attacks of disabling headache and autonomic nervous system dysfunction.This study aimed toassess changes in vasomotor reactivity in migraine patients, and to detect difference in vasomotor reactivity between migraine patients and normal individuals using breath holding index. Patients and Methods: This case-control study was carried out in Neurology Department at Zagazig University Hospital and Neuropsychiatry department at El-Sahel Teaching Hospital Outpatient Clinics during the period from Abril to December 2020. included 2 groups; group A included thirty-two (32) patients suffering from migraine, diagnosed according to the international classification of headache disorders third edition (ICHD-3), while group B included thirty-two (32) apparently healthy individuals, they had their age and sex matched with patients.Results:There was a statistical significance decrease in BHI and Max. FV Lt MCA among sever patients compared to moderate patients. Conclusion: Migraineurs have significantly lower BHI compared to control group, the noninvasiveness of TCD and the possibility it provides for obtaining instantaneous information about cerebral blood flow changes indicates its usefulness in the study of vascular changes in different types of migraine.