Drug Utilization Evaluation of Antibiotics in a Tertiary Care Centre, Bhubaneswar

Abstract

The conventional need for broad-spectrum antibiotics for inorganic infections in hospitals raises the problem of resistance. Most antibiotic use is empirical and results in irrational prescriptions. Our current study aims to gain access to an assessment of drug use for antibiotic use in tertiary hospitals that will facilitate access to rationality and facilitate monitoring of drug effectiveness, cost constraints and other related factors in patient safety. The prospective study was conducted at IMS and SUM Hospital, Bhubaneswar for a period of one year May 2019 to April 2020. A total of 420 cases were analyzed. Among the wide variety of antibiotics, viz. Of the 479 antibiotics prescribed, beta-lactam was detected in maximal cases, that is, more than half of cases.  51.90% received two antibiotics followed by three antibiotic prescriptions. 9.05% of prescriptions are given with 4-5 antibiotics. Careful use of antibiotics will reduce the severity of multiple drug resistance, thus allowing better patient management and limiting the resulting morbidity and mortality.