Formulation and Evaluation of Mosquito Repellent Lotion of Vasaka Stem Extract

Abstract

Medicinal plants contain numerous biologically active compounds which are helpful in improving the life and treatment of diseases and these are the primary source of synthetic and traditional herbal medicine. The presence of various life sustaining constituents in plants made scientists investigate these plants for their uses. The objective of the work was to formulate a mosquito repellent product containing Adhatoda vasica (Acanthaceace). Adhatoda vasica (Acanthaceace) is a well known medicinal plant from which certain alkaloids, phenolics, flavonoids, sterols and their glycoside derivatives have been isolated. Its diverse medicinal activities include cardiovascular protection, abortifacient, antitubercular, antimutagenic, antiulcer, antiasthmatic activities, hepatoprotective, antibacterial and antitussive activities. It is commonly used in indigenous and traditional folk medicine systems in South-East-Asia. The formulation of lotion was evaluated for various parameters like smooth texture and spreadability with a pH 7 which is a non irritant and suitable for the skin. The main evaluation is based on the cage test, cone test which determines the significant result for the activity. There is no phase separation during thermal stability. From the present work, it was concluded that 2ml and 6ml Adhatoda vasica containing lotion is safe, effective, usable for the skin and stable too and gives an effective result after the 4.0 and 4.5 intervals after application. The conclusion from the research, determines the potential to provide efficiency and can be used as a cheap, eco-friendly, safer for humans and the environment and also an efficient alternative to the chemical mosquito repellent.