Main Article Content
Nanoparticle based formulations have been gaining importance due to their targeted delivery, increased skin permeability and control release for the treatment of skin infections. The nano- ointment of grapheme conjugate with usnic acid was prepared with water soluble base and was subjected for anti-fungal activity by using fungal strain Candida albicans. The in-vivo anti-fungal activity shows significant (p<0.001) anti-fungal activity that corresponds similar to activity of standard marketed preparation. This significant anti-fungal property shows synergistic response of both the drug and carrier as reported for their anti-microbial property.