Histological and Cytological Alteration of Gastrointestinal Tract in Patients with COVID 19

Abstract

In Wuhan, China, known as Covid19, a novel corona virus was first identified as the cause of SARS2 disease at the end of 2019 in December, resulting in pneumonia, failure of most respiratory systems and causing mortality. There is no question that Covid19 is mainly regarded as an infectious respiratory disease with a range of respiratory complications resulting in death abroad, but the findings of symptoms and histological damage to the gastrointestinal tract could be linked with digestive system involvement in Covid19. According to several previous studies, in addition to the establishment of infiltration of lymphocytes and plasma cells through the interstitial connective tissue of mucosal lamina properia, corona virus RNA2 was observed in the faeces of asymptomatic person, degeneration and shedding of the mucosal epithelial layer of most sections of the food tube. Gastric and intestinal viral tropism due to the presence of ACE2 receptors has been documented.

Within the current study, we review the foremost critical of microscopical gastrointestinal alterations in connection with this novel disease.