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Bispyribac-sodium (a herbicide in rice fields). We explore the cytotoxic impact of bispyribac sodium in pale skinned person female rodents that intubated orally with 40 and 80 mg/kg of bispyribac sodium for thirty days. It was discovered that bispyribac herbicide caused critical decline in the body weight acquire proportion of pale skinned person rodents. Also, bispyribac sodium indicated huge decrement in the Hb, RBCs, PCV and raised level of WBCs. Conversely, bispyribac herbicide expanded huge degrees of AST, ALT and ALP in compare with control group. Additionally the outcomes demonstrated critical expansion in MDA level and huge decline in SODand GPX levels. Inconclusion, the utilized of bispyribac sodium for quite a while have an unsafe impacts in all the body organs coming about because of collection on it.