Immunological Parameters in Patients with Chronic Cystic Sinusitis

Abstract

Diseases of the paranasal sinuses (DPN) are the most common pathology in otorhinolaryngology. According to the literature, it is known that cystic sinusitis is an infectious and allergic disease, and the formation of cysts is considered as the result of an allergic reaction to infection in sensitized patients. Adverse environmental impact on the immunological system of the human body, reducing natural resistance, increasing the degree of allergization of the population contributes to increased rate of respiratory diseases. In this regard, it is relevant to study the indicators of immunity in patients with chronic cystic sinusitis. We examined 138 patients with chronic cystic sinusitis aged 17 to 64 years. Conducted immunological study of the state of cellular and humoral immunity in accordance to recommendations of the Institute of Immunology. A comprehensive immunological examination revealed a sharp imbalance of immunological parameters in serum, nasal flushes and cystic fluid in patients with chronic cystic sinusitis. In addition to etiological and pathogenetic treatment in patients suffering from chronic cystic sinusitis, it is necessary to include immunodulators and immunostimulators.