Screening Of Phytochemicals, Invitro Assessment Of Antioxidant, Anti-Inflammatory, Tlc Profiling And Anticancer Activity Of Aegle Marmelos (L.) Leaves

Abstract

   The current study is aimed to evaluate the efficacy of methanolic extract of Aegle marmelos leaves for pharmacological properties. The qualitative phytochemical analysis was determined. The antioxidant and anti-inflammatory properties were analyzed using different assays. The TLC profiling was also determined to study the various phytochemicals. The MCF-7 cell lines were assessed for anticancer property. The phytochemical analysis revealed the presence of alkaloids, flavonoids, phenols, steroids, tannins, saponins, terpenoids and glycosides. The DPPH and ferric antioxidant reducing assay showed that the antioxidant capacity of the methanolic extract of A. marmelos leaves increased in a dose dependent manner. The anti-inflammatory activity using protein denaturation assay showed promising results. The TLC analysis exhibited the presence of different phytochemicals and the retention factor was also calculated. The anticancer activity in MCF-7 cell line significantly reduced the viability of the cancer cells in dose dependent manner. Hence, from this study the methanolic extract of A. marmelos can furthermore be explored for pharmacological properties.