Main Article Content
Vildagliptin is an oral antihyperglycemic agent which is incorporated in the osmotic controlled release drug delivery system. Drug passes all the parameters of preformulation studies. Vildagliptin is compatible with other excipients analysed by various studies like FTIR analysis.
Core tablet is prepared by wet granulation technique with composite formula by 3/2 factorial design. Core tablet is coated with spray technique using described coating solution.
According to post compression parameters like dissolution test, SEM and stability study F7 is optimized formulation which shows 97.32 % drug release after 12 hrs.