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Introduction: The regenerative endodontic procedure (REP) is considered as a viable treatment option for immature teeth with necrotic pulp caused due to trauma.
Aim: A clinical trial was designed to evaluate the efficacy of blood clot and injectable PRF on root maturogenesis of immature permanent teeth.
Materials and Methods: Ten children of 8-13 yrs. age group were included in the study. After access opening, irrigation with 1% sodium hypochlorite and Tri-antibiotic paste was placed in the teeth. After 3 weeks, the cases were divided into two groups with five patients in each. Group I in which blood clot was induced and Group II injectable PRF was placed in the root canal as a scaffold.
Results: Injectable PRF induced greater root lengthening, shortened the healing of soft and hard tissues than blood clot in root maturogenesis.
Conclusion: Injectable PRF was more effective in root maturogenesis of non-vital immature permanent teeth compared to the blood clot.