To Study the Effectiveness of Platelet Transfusion in Management of Dengue Patients in Tertiary Care Hospital

Abstract

Background:-

Dengue has been emerging as rapidly spreading and dreaded mosquito borne diseae caused by the bite of Aedes Aegypti Mosquito. Clinical features are variable and presents with Dengue fever or Dengue Hemorrhagic fever or more severe  Dengue shock syndrome. Thrombocytopenia is presenting feature in in all Dengue cases and some often presents with bleeding. Platelet transfusions are given in patients with haemorrhagic symptoms.

Present study thus aims to study the effectiveness of platelet transfusion in management of Dengue patients with Dengue haemorrhagic fever and Dengue shock syndrome.

Results: In present study , a total of 20 patients were diagnosed as dengue confirmed cases by serological testing methods. Out of 20 , 12 (60%) patients had   dengue fever with platelet count in range of 50,000-80,000/µl. Two  patients with   Dengue fever had    Petechial spots  with platelet count in range of 50,000/µl and   were given prophylactic Single Donor  Platelet Transfusions. Eight patients (40%) presented with Dengue Haemorrhagic fever and platelet count of < 20,000/µl . These patients  were given single donor platelet transfusions. Six patients responded good with CCI of > 30,000/ µl and 2 patients recorded as non responders.

Conclusion:-This study suggests that 25% Platelet transfusions are inappropriate. Platelet transfusions are more effective when it is given to patients with platelet count < 20,000/µl. Platelet transfusion should be given based on platelet count and hemorrhagic manifestations ,  as this decreases hospitalization of patients and complications of dengue.

Topic:- To  study the effectiveness of platelet transfusion in management of Dengue Patients in tertiary care hospital.