Electrochemical sensor for determination of Dopamine based on MnCr2O4 nanocomposites modified carbon paste electrode

Abstract

MnCr₂O₄ nanocomposites/modified carbon paste electrode based sensor were developed and validated by electrochemical detection of dopamine (DA). Hydrothermal method was used to prepare the MnCr₂O₄ nanocomposites. Various approaches were used to characterize the Synthesized MnCr₂O₄ nanocomposites. Cyclic voltammetry was used to investigate the redox properties of MnCr₂O₄ nanocomposites/modified carbon paste electrode (MnCr₂O₄ nanocomposites/MCPE). The oxidation and reduction peak occurred at pH7.4 with the supporting electrolyte being 0.2M phosphate buffer solution in the analysis of MnCr₂O₄ nanocomposites /MCPE. The MnCr₂O₄ nanocomposites/MCPE has a very low detection limit is 0.63 µM, high sensitivity, a large surface area, a wide linear range (10 mM to 100 mM), and good repeatability. This modified electrode, which was used to detect dopamine in injection samples, has a lot of promise in practical applications.