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Rhinosinusitis with orbital complications is an emergency that not only threatens vision but also life. One of its serious complications is brain abscess.Antibiotic treatment may fail as this surgical intervention may be necessary and mandatory to perform an endoscopy.Four patients with orbital cellulitis over sinusitis were included in the study from 2013-2014. All of them did not respond to the medical administration and thus were conducted to them endoscopic sinus surgery, 3 of them had successful results and their health condition improved within one week of endoscopy, and one of them improved after the operation, but she had a relapse and died. We conclude that antibiotics do not treat and do not serve all pathological conditions, especially those that have complications.Excellent results and no major complications can be recommended for endoscopic sinus surgery.