Seroprevalence of Anti-Phospholipid Igm and Igg Antibodies in Aborted Women Carrier with Herpes Simplex Virus Type 2

Abstract

Background: The existence of anti-phospholipid antibodies produces a prothrombotic states and elevated risk of pregnancy complications. Objective: the existing study aimed to detect the rate of anti-phospholipid IgM and IgG antibodies in aborted women carrier with Herpes simplex virus type 2 and compared with pregnant women. Patients and methods: The current study done on 120 women who include 60 aborted women and 60 pregnant women as a control group, the age of both groups are ranged from 15-43 years. The blood samples are obtained from both groups and then centrifuged to obtain the serum that used for detection of HSV-2IgM and anti-phospholipid IgM and IgG antibodies. Results: Within aborted women group, about 13(61.9%) and 30(76.9%) aborted women carrier with HSV-2 seropositivity have seropositive anti-phospholipid IgM antibody existent in ≤6 weeks and more than 6weeks respectively while in non-aborted group there was only 2(6.3%) positive anti-phospholipid IgM antibody. There was no significant relation between apl IgG and cases in all gestational age groups (P>0.05). Conclusion: The most antiphospholipid IgM antibody seropositivity observed in aborted women’s serum at gestational age more than six weeks. There was no significant relation between seropositivity of anti-phospholipid IgM antibody with number of abortion.