Main Article Content
As the utilization and abuse of substance often starts in adolescence posing threat to public health concerns. Rising trend with growing popularity of various substances in the past decade, include heroin, kratom, cannabis, ketamine and methamphetamine which recorded highest usage in year of 2019 in Malaysia. Research reviewed includes clinical manifestation, statistics, and treatment with types of substance abuse and meeting future challenges in Malaysia. Study on pharmacological treatment for substance abuse were found to be effective in terms of compliance, relapse rate and cost effectiveness by providing methadone or buprenorphine to minimize heroin dependent problems.