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Background:Wound healing is a response to tissue damage that includes both molecular and cellular processes for tissue repair. In several studies, it is often found substances in plants that help in the process of stopping bleeding such as flavonoids, saponins, and tannins. These three ingredients are owned by Kepok banana peels(Musa paradisiaca L.).Flavonoids have an effect on capillary blood vessels, saponins have a hemostatic effect by reducing blood clotting, and tannins can have a vasoconstrictive effect on capillary blood vessels. In Kepok banana peel waste, it is found that the content of saponins, alkaloids, tannins, and flavonoids.Objective:To make systematic review the banana peel extract’s content as a hemostasis in wound healing.Methods:The data was collected by searching the literature on article search sites, namely Google, Pubmed and Science Direct which were published from 2011 to 2021, the search was carried out in January 2021. The data search was carried out systematically using keywords wound healing, banana peel extract.Result:After eliminating duplicate articles, the titles and abstracts of each article were analyzed across 122 articles excluding 94 articles. The full-text articles in the remaining 10 articles were analyzed again and 28 articles were excluded.Conclusion:Recent literature shows that the extract content of banana peels has been described as having bioactive compounds which can be an alternative in wound healing.