The Detection for Some Biological Indicators in Blood Specimens of Alzheimer’s Disease

Abstract

Alzheimer’s disease (AD) is the most important cause of dementia in the elderly. The molecular alterations preceding this neurodegenerative pathology may take place even 20 years before its clinical appearance. This study discusses the detection for some biological indicators (Complete Blood Count, Total fat percentage, Sugar and Insulin, kidney and liver function, and Thyroid hormone functions) in blood specimens of Alzheimer’s disease, where they included 42 patients suffering from Alzheimer's disease after confirming their diagnosis of the disease and 30 cases as health controls. after the examination observed clear changes in the measurement of some biological indicators of patients compared to healthy subjects, which showed significant differences such as the number of white blood cells, lymphocytes, red blood cells, hemoglobin, hematocrit and triglycerides, and we did not notice any changes in the levels of lipids (cholesterol, LDL, HDL), as well Kidney and liver function, where no significant differences were found. Through the statistical analysis, also, it was observed that there was a significant decrease in the mean values of TSH and T4 hormones in the patients compared to the healthy controls, as well as a slight decrease in the mean values of T3 hormones in the patients.