Comparative Analysis and Synthesis of Silver Nanoparticles from Selected Parts of Mimosa Pudica to Treat Urinary Tract Infection

Abstract

Mimosa pudica L. is an annual herb that is known for its sensitive nature. This plant is now growing as a weed in mostly all the countries. It has been known to have antibacterial, antifungal, antiviral, antioxidant, anti-inflammatory, anti-asthmatic, analgesic and anti-depressant activities and thus is widely used in herbal medicine. In the present study, the antimicrobial activity of ethanol extract of parts of Mimosa pudica (leaves, stems and roots) was compared with the extract infused with the synthesis of silver nanoparticles against various pathogenic bacteria causing UTI (Urinary Tract Infection) such as Escherichia coli, Pseudomonas aeuroginosa, Enterobacter, Proteus, Staphylococcus saprophyticus, Citrobacter, Klebsiella, and Enterococcus aureus at different concentrations and was analyzed with the crude ethanol extract.. The surface topography and composition of the sample is detected by using SEM (Scanning Electron Microscope), Infrared spectrum of absorption, emission. The stability of colloidal dispersion is analyzed by Zeta potential and for the presence of interfering substance Ultraviolet-visible spectroscopic method is also used. At the end, silver nanoparticles showed a maximum zone of inhibition than normal ethanol extract against UTI pathogens which implied that synthesis of silver nanoparticles from the plant extract may be helpful in the treatment of UTIs.