Effect of Demographic Data on the Outcome of Chronic Hemodialysis in Children, A Multicentric Study

Abstract

Background :The use of chronic dialysis to sustain the lives of children with end-stage renal disease(ESRD) has been available in developed countries for more than 30 years. During the past few decades , advances in technology have made long-term dialysis a viable treatment option for pediatric ESRD patients of all ages, from newborns to adolescents.While a successful kidney transplant remains the treatment of choice for all pediatric ESRD patients, almost three-fourths of these children require chronic dialysis while awaiting transplantation for periods ranging from a few months to several years . Pediatric dialysis carries a significantly higher mortality than that for the age – adjusted population. Objectives:-To know the effect of demographic data on 4 years outcome of pediatric patients on chronic hemodialysis program. Patients and Methods:- A cross – sectional study of all chronic hemodialysis patients who started dialysis in pediatric age, in hemodialysis centers in Al Kharkh side of Baghdad city extendedbetween the 1st of January of 2011 to 31th ofDecember 2014. During which 94 patients were collected. Clinical and laboratory data were obtained from medical records and by direct interview with each patient by questionnaire. The questionnaire include variables in the patients demographics data and factors that may influence outcome.
Causes of death was taken from the pediatric nephrologist of each center data was observed and analysis was carried out using spss-21. Result:-During the period of the study, a total of 94 patients on chronic HD program were studied according to patients demographics data, where the age group ≤ 7 years were (26.6%) while these ≥ 14 years were (7.44%). Male form (63.82%) while female (36.17%). (75.5%) of patients were from Baghdad city. The cause of end stage renal disease was small size kidneys (15.95%), unknown causes ( 13.82%), urological problems (29.59%), SRNS were (11.70%), Cystinosis were (6.38%), recurrent renal stones (6.38%) and (19.14%) were due to other causes. The samplestudied according to the effects of these factors on the outcome of the patients on the chronic HD program. Were the primary cause of ESRD have a significant correlation with the patients outcome dead or alive. Overall survival rate was (51.1%). Conclusions:- primary cause of ESRD were associatedwith a significant correlation with the patients outcome.No effect of age at start of hemodialysis, sex, on the outcome of the pediatric patients on chronic HD program enrolled in this study .