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Background: Impulsivity is a multifaceted construct known to play a crucial role in the development and maintenance of a wide range of problematic behaviors and psychological disorders in children. Aim of the study was to assess self-regulation skills of preschool children with impulsivity attending nursery schools. Subjects and Methods: Research design: A cross-sectional descriptive research design was used. Setting: The study was conducted at two nursery schools in" Diarb Negm" city, Sharkia governorate, Egypt. Subjects: A purposive sample of 150 children was recruited for the study. Tools of data collection: three tools were used in the present study; A structured interview questionnaire, Matching Familiar figure Test (MFFT) scale, and Self-regulation scale from the Child Self-Regulation & Behavior Questionnaire (CSBQ).Results: Findings revealed that 33.3% of children in the total study sample were impulsive. Nearly half of the study sample had deficient self-regulation skills. Also, a highly statistically significant relationship was found between impulsivity and self-regulation skills. Conclusion: lack of self-regulation skills was associated with impulsivity, with statistically significant relation. Recommendations: self-regulation training programs should be implemented to enhance impulsivity among preschool children. Further researches should be developed to address the risk factors of impulsivity and poor self-regulation skills and how to manage them.