Current Status of Plasma Therapy in the Pandemic Corona Virus Disease-19: A Therapeutic Alternative for Patients

Abstract

Currently, the transfusions of convalescent plasma are widely used in the pandemic corona virus disease-19 (COVID-19). The use of plasma lacks a specific prevention and therapy of this virus disease. Thus, the treatment using plasma has a meticulous interest till specific vaccine is not offered for control and management of viruses. During the infection, severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) identified which is responsible to cause COVID-19.This paper reviews from literature available on Google scholar, pub Med, Scopus database and focused on the use of convalescent plasma as one of the therapeutic alternative for management of COVID-19. The convalescent plasma can be immediately used in such treatment which establishes quick convenience of a capable therapy before validation of the vaccines and specific therapy are for appropriate scaling. Further, literature is searched to develop better convalescent plasma. The development of vaccines and more specific therapeutic agents is based on the availability of extensive data from studies of disease’s pathogenesis and its immune response. In addition, margin of safety is requisite to defend the convalescent plasma recipients because of lacking more information on natural history of the disease.