Study of Lipid Profile and Liver Function Test as Potential Markers with Severity of Dengue Fever

Abstract

Dengue fever (DF) is normally a self-restricting mosquito-borne viral illness. It is brought about by one of the 4 subtypes of the dengue infection. It is a solitary positive abandoned RNA infection. The essential dengue infection was gotten from fighters who turned out to be sick in Calcutta, New Guinea, and Hawaii. Trademark highlights are fever and insignificant protected indications, the inclination to stun and drain, or dengue stun disorder/dengue hemorrhagic fever (DSS/DHF). Preceding the historical backdrop of the Jin Dynasty of Dengue, it was in the past known as a water poison suspected to be spread by the blowing of air. The target here is to correspond biochemical changes in lipid profile and liver capacity tests with seriousness in dengue disease. The technique we have embraced for our examination is done on patients experiencing dengue fever who were conceded for over year and a half at Krishna Hospital and Medical Research Center, Karad. According to WHO, there are 390 million Dengue infections per annum, of which 96 million manifests clinically with severe disease. Result Majority of the patients were diagnosed as Dengue Fever (54.4%), followed by Dengue Haemorrhagic Fever (37.8%) and Dengue Shock Syndrome (7.8%). There were 42 patients (46.7%) with ALT less than 50 and 31 patients (34.4%) with AST less than 50. There were 19 patients (21.1%) with ALT 50 to 150 and 25 patients (27.8%) with AST 50 to 150. The study concludes that Dengue viral fever is one of the common viral infection requiring hospitalization. The clinical features of Dengue fever can widely vary from mild fever, minimal constitutional symptoms to features like severe bleeding tendencies, shock, acute respiratory distress syndrome (ARDS) and even death.