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Probiotics can be defined as the group of microorganisms having beneficially effects for health if they encounter with an appropriate amount. They provide vital metabolites with nutritional and therapeutic properties that provide countless health benefits. Probiotics have been demonstrated toprevent somedigestive disorders such as infectious diarrhea, helicobacter pylori infection, antibiotic-associated diarrhea (AAD), necrotizing enterocolitis(NEC), chronic kidney disease (CKD), Irritable Bowel Syndrome (IBS). The most widely used probiotic species areBifidobacterium and some lactic acid bacteria strainsthat are used in wide range of functional foodsas well as in dietary supplements. For sake of an additional information , probiotics are responsible for treatment of several disorders like type 2 diabetes, non- alcoholic fatty liver dysfunctions also acts an co adjuvant many metabolic diseases and in obesity too. Therefore, the action mechanismof probiotics includeddiversified, strain speciﬁed as well as miscellaneousthat have examined some monitoring. The main focus of the research is to reconsideration Probiotics‘s assorted action mechanisms.Further attempts have been made to isolate the new probiotics from unexplored microflora and to investigate their mechanisms of action.