Evaluation of Aspartate Aminotransferaseto-Platelet Ratio Index as a Non-Invasive Marker for Liver Cirrhosis

Abstract

Background :For Cirrhosis of liver the gold standard diagnosis is liver biopsy .Till now no non-invasive marker has been invented to replace liver biopsy.

Objectives :

To correlate APRI with the rigorousness of cirrhosis with meld and child PUGH score.

To correlate APRI with various etiologies of cirrhosis.

To corelate APRI with various outcome of cirrhosis in terms of mortality and morbidity.

Method : The Prospective cross-sectional study will be conducted  at  Department of Medicine, in AVBRH, situated at Wardha District. We will prospectively enroll all consecutive patients > 18 years of age apart from  gender or ethnicity who undergo irrefutable, biochemical and radio diagnostic testing for cirrhosis

Expected results : The study estimates the APRI in patients of cirrhotic liver disease and as previous studies which is been conducted outside India, have observed that APRI can be used to identify cirrhosis in different patient who undergone study.