CELIAC DISEASE and the Molecular Detection of Imbalances Through the use of a High-Precision Method

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Mohammed Abdulfatah Al-Ayash, Abbas A. J. AL-Salihi, Rusul Muzher Hussein, Rana R. AL-Saadi, Ban Thabit Saeed

Abstract

Celiac disease (gluten enteropathy, enteropathy, and J-Herter-Heubner disease) - pathological disorders of the intestine, in which there is an intolerance to gluten. As 70 samples were collected from patients, the aim of which was to know the molecular detection of the disturbances occurring through the use of the accurate method, which is SYBR Green technicality with melting curve analysis on genomic DNA Isolated and  for the control samples, it consisted of 30 samples, The increase in mortality from all diseases in the group compared to the initial period from 62 to 77% was a limited value without a clear correlation and only confirmed the trend of increase in total deaths from all causes from 1.37 to 1.57, excluding deaths from cardiovascular disease. , Although in half of the cases it was related to celiac disease. In the structure of mortality, an increase in respiratory diseases is observed during the period of application of serological diagnostics

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Mohammed Abdulfatah Al-Ayash, Abbas A. J. AL-Salihi, Rusul Muzher Hussein, Rana R. AL-Saadi, Ban Thabit Saeed. (2021). CELIAC DISEASE and the Molecular Detection of Imbalances Through the use of a High-Precision Method. Annals of the Romanian Society for Cell Biology, 11314–11324. Retrieved from https://www.annalsofrscb.ro/index.php/journal/article/view/3909
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