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This study was done to evaluate the degree of microalbuminuria in sepsis in correlation with SAPS II Score and to test whether the degree of microalbuminuria could predict mortality in critically ill sepsis patients. The present study conducted on patients admitted to Medical ICU/Medical emergency ward, 64 patients who meet the inclusion and exclusion criteria were included in the study. The degree of Microalbuminuria was more among patients with organ dysfunction than those without. Significant microalbuminuria was indicative of Multi organ Dysfunction. Serial measurements may help in the clinical assessment of critically ill patients at risk of worse prognosis, even in resource poor areas.