Evaluation of Nesfatin – 1 and Other Biochemical Markers in diabetic Neuropathy Iraqi patients before and after treatment with tegretol

Abstract

Diabetic neuropathy is a form of nerve damage that can occur in people who have diabetes. High blood sugar (glucose) induced nerve damage in every part of the body. The nerves in the legs and feet were the most frequently affected. The extent to which a diabetic patient's body is impaired is calculated by the degree of nervosa harm.The purpose of this present study is estimation  BMI,IL-10 , nesfatin-1 and HS-CRP  in Iraqi DN patients  before and after   treatment via tegretol as well  as it is the first  study sheds light  on the relationship between Nesfatin -1 and other  parameters ( BMI,IL-10 and HS-CRP) also predication of Nesfatin-1 as  a newly biomarker in patients with   diabetic  neuropathy. The present study consist of from 30 cohort  G1 as  healthy group the age range from (30-50 ) years while diabetic neuropathy patients was  divided into subunit group one of them before treatment  (G2) age range (30-60 ) years   whilst  group 3(G3) age range ( 30-60 ) years after treatment ,from the results we  concluded the effect  of treatment by tegretol  on BMI ,IL-10 and HS-CRP , but we found non-significant this treatment   on Nesfatin-1 levels  for  patients undergo with tegretol treatment   this indicated that Nesfatain -1 can't be utilize as a biomarker in those patients