Extract of 75% and 95% Chromolaena odorata Effective to Reduce Bleeding Time of Acute Wound: Traditional Wound Care Approach

Abstract

Chromolaena odorata is a plant containing tannins, phenols, flavonoids, saponins, and steroids. They were traditionally used as a remedy for bleeding cessation. This research to knows the difference in the effectiveness of Chromolaena odorata extract 75% and 95% to bleeding time of acute wounds. Research used an experimental approach with posttest only control group. The research was conducted at the Laboratory of the Faculty of Medicine, Unversitas Muhammadiyah Surakarta. Samples were 48 Rattus norvegicus, consisting of 16 samples/group. A  random sampling technique was used to select the sample. The instruments were an observation sheet and stopwatch. Data were analyzed using the Mann Whitney test. The mean of the bleeding time in the control group, extract of 75% Chromolaenao odorata group, and extract of 95% Chromolaenao odorata were 1.17 seconds, 0.23 seconds, and 0.20 seconds. Among the three groups, extract 75% and 95% groups effectively reduce the bleeding time (p=0.000). There was a significant difference using an extract of 75% and 95% Chromolaenao odorata to bleeding time (p= 0.000). Extract 75% and 95% Chromolaenao odorata effectively reduce bleeding time in an acute wound. Extract of 95% Chromolaenao odorata was the most effective to reduce bleeding time in a new wound.