Serum Protein Electrophoresis Plays a Role in the Diagnosis of Multiple Myeloma in Baghdad City Patients.

Abstract

Multiple Myeloma (M.M) is an uncontrolled accumulation of irregular plasma cells that is described by a cell line neoplasm B, which secretes abnormal immunoglobulin, which triggers monoclonal gammopathy, identified by the occurrence of M protein in serum, and the aim of this study To define, measure, and distinguish between monoclonal gammopathy and benign disorders in reported cases of multiple myeloma, since the prognosis and treatment, vary widely from each other. The method of the serum samples for 112 alleged cases was divided into two parts, males and females, and the number of males in this study was 56, and the same number of females is subject to cellulose acetate strip serum protein electrophoresis. Visually sensed M band and densitometer estimated M protein. In M band positive cases, bone marrow biopsy and clinical profile have been associated in Serum Protein Electrophoresis by SEBIA Capillarys company, and the result of 112 instances of monoclonal gammopathy was diagnosed. A multiple myeloma diagnosis was rendered in percent of cases, and an undetermined case of monoclonal gammopathy was identified. Conclusion of this survey SEBIA is an easy-to-use laboratory procedure in diagnosis serum protein electrophoresis that is used to diagnose and measure monoclonal gammopathy and can be prescribed for confirmed multiple myeloma cases as a preliminary test.