Evaluation of In-Vitro Antioxidant Activity in Senna Alata of Hydroalcoholic Extract and Methanolic Extract

Abstract

Background: Free radicals, also known as highly reactive oxygen species, can cause oxidative damage to the human body. Antioxidants are molecules that avoid reactive species from attacking the body and reduce the risk of disease. Both Senna alata extracts are used to treat brain diseases in humans and have almost identical effects.

Objective: Senna alata's antioxidant properties were investigated in this review.

Results: The antioxidant function of Senna alata medicinal plants was assessed using DPPH, Reducing power assay, ABTS assay, and Nitric oxide assay methods to ascertain reducing potential and free radical scavenging capacity. Antioxidant inhibitory concentration percentages were also assessed in two extracts (Methanolic extract and hydroalcoholic extract) and found to vary significantly in antioxidant values. The hydroalcoholic extract of Senna alata whole leaf powder had slightly higher antioxidant activity than the methanolic extract.

Conclusion: According to the findings, daily supplementation with hydroalcoholic extract of Senna alata may be more beneficial than methanolic extract in the treatment of neurological disorders caused by free radical harm.