Eugenol as Potential Medicine- Review

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Akshaya R., Jayalakshmi Somasundaram, A. K. Anjali

Abstract

 Eugenol is a naturally occurring phenolic molecule that is used in dentistry. Eugenol is also used as a topical anaesthetic agent in dentistry. Moreover it has many pharmacological effects like anaesthetic and analgesic action in dentistry, and also antibacterial, anti-oxidant effects. Eugenol and thymol were found to possess general anesthetic properties. Since it is a phytochemical constituent, it exhibits highly potent anti-cancer activities that have been attributed to their effect on multiple signalling and apoptotic pathways . It illustrates potent antibacterial potential against the numerous strains of gram positive and gram negative bacteria. Eugenol damages the cell membrane and a cell wall which then induces cell lysis in gram positive and gram negative bacteria.It is also used as an irritant, sensitiser, flavouring agent, root canal medicaments in dentistry. Clove oil or eugenol can be used as local anesthetic and also used as an anesthetic agent in several fish species. In this review study, an elaborate role of eugenol as a potential medicine is required. The review of the scientific literature was done in the preparation of manuscript. The systems and databases were searched for relevant articles from Pubmed and Google scholar. Databases of individual  journals were searched for keywords in this review. The aim of this study is to analyse the role of eugenol as potential medicine .The published article  was selected from the year 1980 to 2020. In this review, 47 articles were reviewed. Hence future research should be aimed at identifying different activities of eugenol.

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Akshaya R., Jayalakshmi Somasundaram, A. K. Anjali. (2021). Eugenol as Potential Medicine- Review. Annals of the Romanian Society for Cell Biology, 6250–6260. Retrieved from https://www.annalsofrscb.ro/index.php/journal/article/view/2148
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