Detection of Candida Albicans and its Adherence to Epithelial Cells in Periodontal Health and Disease – A Clinicomicrobiological Study

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Bharathi, Leena Shettar, Anuradha S. K., Srinath L. Thakur, Dr. Shubhi Gupta, Dr. Manasa H. D.

Abstract

Objectives


To detect Candidaalbicans in periodontal health and disease , to check the effect of SRP on Candidaalbicans, invitro to check the adherence of Candidaalbicans to epithelial cells.


Materials and methods


60 subjects between 25-55 years categorized into 2 groupsperidontally healthy and chronic periodontitis. The parameters were checked at baseline and after 15 days, plaque samples were collected to check the presence or absence of Candidaalbicans. Scaling was carried out in chronic periodontitis group. Plaque samples were collected after 15 days in subjects tested positive for Candidaalbicans at baseline and  invitro adherence  was checked in them.


Results


Candidaalbicans were present in 4 subjects and in vitro study showed adherence Candida albicans to epithelial cells.


Conclusion


Candidaalbicans is present in the chronic periodontitis subjects. There is adherence of Candidaalbicans to epithelial cells in chronic periodontitis patients. Futher the role of different species of Candida in periodontal disease and in perimplantits, at varying pocket depths, the use of antifungal therapy in unresponsive cases needs to be evaluated.

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How to Cite
Bharathi, Leena Shettar, Anuradha S. K., Srinath L. Thakur, Dr. Shubhi Gupta, Dr. Manasa H. D. (2021). Detection of Candida Albicans and its Adherence to Epithelial Cells in Periodontal Health and Disease – A Clinicomicrobiological Study. Annals of the Romanian Society for Cell Biology, 5329–5341. Retrieved from https://www.annalsofrscb.ro/index.php/journal/article/view/2038
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