Challenges in the synthesis of n-CoV vaccine - A review

Abstract

This review highlights the challenges and difficulties faced by the researchers towards the synthesis of the n-CoV vaccine.The articles were collected from search engines like PubMed, Google scholar, Biorxiv, MedRxiv, Cochrane, and also two primary Chinese databases were used for biomedical research namely CNK1 and WanFang. The relevant articles were collected from the period from 2000 to 2020 to date. This review reveals that the COVID vaccine will be soon discovered in spite of potential obstacles. Phase I of the nCoV vaccine was successfully done. Scientists and Physicians are drilling down to establish an effective vaccine to eradicate this pandemic threat CORONAVIRUS by inculcating different guidelines for the synthesis of vaccines.In the current background of the SARS CoV-2 pandemic, population immunization by vaccination is recognized as a priority for public health. The clinical safety and effectiveness proof is considered as the most important scientific obstacles. This review thus highlights the various challenges in the design, evaluation, and synthesis of n-CoV vaccines.