Ethnopharmacological Investigation of Some E Medicinal Plants for the Management of Nephrotoxicity

Abstract

Traditional systems of medicine, especially Ayurveda contains number of preparations for treating liver & GIT disorders. In the present study deals with investigation of some medicinal plants for the management of nephrotoxicity of plant. For study we used leaves extract of A. cordifolia , leaves extract of Cyathea gigantea and seed extract  Persea Americana seed in 1:1:1 ratio. We have evaluated the nephroprotective  activity of combination of  extracts  by selecting experimental models which included gentamicin-induced nephrotoxicty in rats. Our study proved that this combination of plant extract possess considerable amount of flavonoid and phenolic compounds. In-vivo nephroprotective  activity results obtained also  provided sufficient scientific evidences about the use of CE combination of plant extract (The leaves of A. cordifolia , leaves of Cyathea gigantea and  seed Persea Americana seed) for the treatment of drug induced kidney injury.