A Comparative study of Total Intravenous Anaesthesia using Propofol and Fentanyl with Standard Balanced Anaesthesia Technique using Isoflurane in Short Stay Surgical Procedures

Abstract

Background:In most procedures, total intravenous anaesthesia (TIVA) and balanced anaesthesia are employed. The goal of our study was to assess the recovery features, haemodynamic alterations, and any adverse effects in day care procedures across two groups: TIVA using propofol + fentanyl and Balanced anaesthesia using propofol and isoflurane.

Material and methods: This randomized study was undertaken on sixty ASA grade I and II patients of 20 -60 years age, of either sex, weighing 40 -70 kg , divided into two groups of thirty each.

Group I patients were induced with propofol 2.5 mg/kg plus fentanyl 3 µ gm/kg. The airway was maintained with 100% oxygen by facemask with continuous propofolinfusion

Group II Induction was done with propofol 2.5 mg/kg and fentanyl 3 µgm/kg. Intubation was done with Suxamethonium 1.5 mg/kg. I.V. Anaesthesia was maintained on Isoflurane 1% and nitrous oxide:oxygen: 70:30.Injection Vecuronium 0.05 mg/kg was used for muscle relaxation.

Results:Modified PADSS score≥9 was achieved in both groups at 1 hour (P=.129).The patients in Group I had smooth recovery with no history of cough or postoperative nausea vomiting. Therefore, TIVA is better choice of anaesthesia in Day care surgeries.The patients in group I were haemodynamically more stable at 0 min, 5 min, 40 min, and 50 min after induction(P<0.05)

Conclusion: TIVA is a better choice as compared to balanced anaesthesia with Isoflurane in day care surgeries.