Biological Activity and Antiproliferative Assay of Fish Mucuspeptides

Abstract

 Antimicrobial proteins (AMPs) are small cationic or amphipathic proteins, they have capability to interrupt microbial cell membranes by associating negatively charged phospholipids.The mixed cationic and hydrophobic composition of AMPs makes them well suited for interacting with and penetrating microbial phospholipid bilayer.In the current research,the fish mucus AMPs of bacterial infected fishes displayed significantantibacterial,antifungal and anti-cancer properties. This broad antimicrobial and anticancer properties of fish mucus peptides makes them potent therapeutic agents.